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| Therapy Name | PF-08046031 |
| Synonyms | |
| Therapy Description |
PF-08046031 is an antibody-drug conjugate (ADC) comprising an antibody targeting CD228 linked to monomethyl auristatin E, which potentially induces cytotoxicity against CD228-expressing tumor cells and inhibits tumor growth (Cancer Res (2025) 85 (8_Supplement_1): 2959). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| PF-08046031 | PF08046031|PF 08046031 | PF-08046031 is an antibody-drug conjugate (ADC) comprising an antibody targeting CD228 linked to monomethyl auristatin E, which potentially induces cytotoxicity against CD228-expressing tumor cells and inhibits tumor growth (Cancer Res (2025) 85 (8_Supplement_1): 2959). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06799533 | Phase I | PF-08046031 | A Study to Learn About the Study Medicine Called PF-08046031 in Advanced Melanoma and Other Solid Tumors | Active, not recruiting | USA | SWE | GBR | FRA | ESP | 0 |
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