Therapy Detail
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| Therapy Name | DT-7012 |
| Synonyms | |
| Therapy Description |
DT-7012 is a monoclonal antibody targeting CCR8, which potentially induces antibody-dependent cellular cytotoxicity (ADCC) and depletion of CCR8-positive regulatory T-cells (Cancer Res (2025) 85 (8_Supplement_1): 312). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| DT-7012 | DT 7012|DT7012 | CCR8 Antibody 13 | DT-7012 is a monoclonal antibody targeting CCR8, which potentially induces antibody-dependent cellular cytotoxicity (ADCC) and depletion of CCR8-positive regulatory T-cells (Cancer Res (2025) 85 (8_Supplement_1): 312). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06819735 | Phase Ib/II | DT-7012 DT-7012 + unspecified immune checkpoint inhibitor | Study of DT-7012 as a Single Agent and in Combination With an Immune Checkpoint Inhibitor in Participants With Advanced Solid Tumors (DOMISOL) | Recruiting | AUS | 0 |
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