Therapy Detail
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| Therapy Name | KLN-1010 |
| Synonyms | |
| Therapy Description |
KLN-1010 is an envelope-modified lentiviral vector designed to transduce T-cells in vivo and modify them to express a chimeric-antigen receptor (CAR) targeting TNFRSF17 (BCMA), which potentially decreases tumor growth (Cancer Res (2024) 84 (6_Supplement): 48). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| KLN-1010 | KLN1010|KLN 1010|KLN 001|KLN-001|KLN001 | TNFRSF17 Immune Cell Therapy 27 | KLN-1010 is an envelope-modified lentiviral vector designed to transduce T-cells in vivo and modify them to express a chimeric-antigen receptor (CAR) targeting TNFRSF17 (BCMA), which potentially decreases tumor growth (Cancer Res (2024) 84 (6_Supplement): 48). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07075185 | Phase I | KLN-1010 | A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma (inMMyCAR) | Recruiting | AUS | 0 |
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