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| Therapy Name | 131I-TLX-101 + Lomustine |
| Synonyms | |
| Therapy Description | |
| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| 131I-TLX-101 | 131I-IPA|TLX101|TLX 101 | 131I-TLX-101 is a derivative of l-phenylalanine radiolabeled with Iodine-131, which is potentially taken up by tumor cells leading to tumor cell cytotoxicity (PMID: 39211520). | ||
| Lomustine | Belustine | CCNU |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07100730 | Phase III | 131I-TLX-101 + Lomustine 131I-TLX-101 | Study of TLX101-Tx Plus Standard of Care (SoC) Versus SoC Alone for the Treatment of Patients With Recurrent Glioblastoma (IPAX BrIGHT) | Recruiting | AUS | 0 |