Therapy Detail
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| Therapy Name | PBA-0111 |
| Synonyms | |
| Therapy Description |
PBA-0111 is an afucosylated monoclonal antibody that targets LRRC32 (GARP), which potentially prevents TGF-beta1-mediated immunosuppression and enhances antitumor immune response (NCI Thesaurus). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| PBA-0111 | PBA 0111|PBA0111 | PBA-0111 is an afucosylated monoclonal antibody that targets LRRC32 (GARP), which potentially prevents TGF-beta1-mediated immunosuppression and enhances antitumor immune response (NCI Thesaurus). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06700070 | Phase I | PBA-0111 | A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors | Recruiting | USA | 0 |
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