Therapy Detail
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| Therapy Name | ZW251 |
| Synonyms | |
| Therapy Description |
ZW251 is an antibody-drug conjugate (ADC) comprising an antibody targeting GPC3 linked to the camptothecin-derived topoisomerase I inhibitor ZD06519, which potentially induces cytotoxicity in tumor cells expressing GPC3 and inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 2658). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ZW251 | ZW-251|ZW 251 | GPC3 Antibody 7 | ZW251 is an antibody-drug conjugate (ADC) comprising an antibody targeting GPC3 linked to the camptothecin-derived topoisomerase I inhibitor ZD06519, which potentially induces cytotoxicity in tumor cells expressing GPC3 and inhibits tumor growth (Cancer Res (2023) 83 (7_Supplement): 2658). |
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07164313 | Phase I | ZW251 | A Study of ZW251 in Participants With Advanced Solid Tumors | Recruiting | USA | 0 |
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