Therapy Detail
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| Therapy Name | OSE 2101 + OSE-279 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| OSE 2101 | EP-2101|Tedopi|OSE-2101|OSE2101|IDM2101 | OSE 2101 is a cancer vaccine comprising HLA-A2+ restricted modified epitopes targeting CEA, ERBB2 (HER2), TP53, MAGE2, and MAGE3, which may result in activity of an immune response, leading to antitumor activity (Journal for ImmunoTherapy of Cancer 2021;9). | ||
| OSE-279 | OSE279|OSE 279 | Immune Checkpoint Inhibitor 150 PD-L1/PD-1 antibody 132 | OSE-279 is a monoclonal antibody that targets PDCD1 (PD-1) and inhibits ligand binding, which potentially enhances antitumor immune response (Mol Cancer Ther (2023) 22 (12_Supplement): C063). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05751798 | Phase Ib/II | OSE 2101 + OSE-279 OSE-279 | Dose-finding and Dose Expansion Study of OSE-279 in Subjects With Advanced Solid Tumors or Lymphomas | Recruiting | FRA | ESP | BEL | 0 |
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