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| Therapy Name | ATP162 + Ezabenlimab + VSV-GP154 |
| Synonyms | |
| Therapy Description | |
| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ATP162 | ATP-162|ATP 162 | Limited information is currently available on ATP162 (Oct 2025). | ||
| Ezabenlimab | BI754091|BI-754091|BI 754091 | Immune Checkpoint Inhibitor 150 PD-L1/PD-1 antibody 132 | Ezabenlimab (BI 754091) is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (J Clin Oncol. 36, no. 5_suppl (February 2018) 212-212). | |
| VSV-GP154 | VSV GP154|VSVGP154 | VSV-GP154 is a vesicular stomatitis virus (VSV) viral vector-based cancer vaccine containing pancreatic adenocarcinoma patient-derived tumor-associated antigen peptides, which preferentially replicates in tumor cells expressing KRAS G12V or KRAS G12D, potentially resulting in tumor cell killing (NCI Drug Dictionary). |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05846516 | Phase I | ATP162 + Ezabenlimab + VSV-GP154 ATP150 + ATP152 + VSV-GP154 ATP150 + ATP152 + Ezabenlimab + VSV-GP154 | A Study to Evaluate ATP150/ATP152/ATP162, VSV-GP154 and Ezabenlimab in Patients With Pancreatic Ductal Adenocarcinoma (KISIMA-02) | Recruiting | USA | ESP | DEU | CHE | 0 |