Therapy Detail
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| Therapy Name | FT836 + Trastuzumab |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| FT836 | FT 836|FT-836 | FT836 is an iPSC-derived CAR-T therapy that targets the alpha3 domain of MICA/B, which may lead to anti-tumor immune response (J Immunother Cancer 2024;12(suppl_2):Abstract 264). | ||
| Trastuzumab | Herceptin | Anti HER2 | HER2 (ERBB2) Antibody 80 | Herceptin (trastuzumab) is a monoclonal antibody, which binds ERBB2 (HER2) to induce tumor cellular cytotoxicity (PMID: 17611206). Herceptin (trastuzumab) is FDA approved for HER2-overexpressing (or amplification) breast cancer, gastric adenocarcinoma, and gastroesophageal junction adenocarcinoma (FDA.gov). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07216105 | Phase I | FT836 + Paclitaxel + Trastuzumab FT836 FT836 + Trastuzumab Cetuximab + FT836 + Paclitaxel Cetuximab + FT836 FT836 + Paclitaxel | FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors | Recruiting | USA | 0 |
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