Therapy Detail
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| Therapy Name | ATO-101 |
| Synonyms | |
| Therapy Description |
ATO-101 is a radioconjugate comprising girentuximab (TLX250), a monoclonal antibody that targets CA9 (CAIX), conjugated to the radionuclide astatine-211, which delivers radiation to tumor cells and potentially results in decreased tumor cell viability (PMID: 40227816). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ATO-101 | ATO101|ATO 101|[211At]At-anti-CA-IX | ATO-101 is a radioconjugate comprising girentuximab (TLX250), a monoclonal antibody that targets CA9 (CAIX), conjugated to the radionuclide astatine-211, which delivers radiation to tumor cells and potentially results in decreased tumor cell viability (PMID: 40227816). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07260162 | Phase I | ATO-101 | Evaluation of Safety, Tolerability and Response of ATO-10 in Patients With Non-Muscle-Invasive Bladder Cancer (PERSEVERANCE EU) (PERSEVERANCE) | Not yet recruiting | FRA | 0 |
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