Therapy Detail
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| Therapy Name | Carboplatin + Nab-paclitaxel + SSGJ-707 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Carboplatin | Paraplatin | CBDCA | Chemotherapy - Platinum 7 | Paraplatin (carboplatin) is a second-generation platinum compound and is activated intracellularly to form reactive platinum complexes that cross link DNA with DNA and with proteins. This induces apoptosis and inhibits cell growth (NCI Drug Dictionary). |
| Nab-paclitaxel | Abraxane | ABI-007|Paclitaxel Protein-bound | Chemotherapy - Taxane 3 | Abraxane (nab-paclitaxel) is an albumin-stablized version of paclitaxel, which binds microtubules and prevents depolymerization, resulting in decreased cell motility and division (NCI Drug Dictionary). |
| SSGJ-707 | PF-08634404|SSGJ 707|SSGJ707|PF08634404|PF 08634404 | PD-L1/PD-1 antibody 136 VEGF Antibody 17 | SSGJ-707 (PF-08634404) is a bispecific antibody that targets PDCD1 (PD-1) and VEGF, which potentially decreases tumor growth (Journal for ImmunoTherapy of Cancer 2025;13, Suppl_3). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|
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