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| Therapy Name | 212Pb-MP0712 |
| Synonyms | |
| Therapy Description |
212Pb-MP0712 is a radioconjugate comprising a designed ankyrin repeat protein (DARPin) that specifically binds DLL3 conjugated to the radionuclide 212Pb, which potentially inhibits tumor growth (Cancer Res (2025) 85 (8_Supplement_1): 346). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| 212Pb-MP0712 | MP-0712|MP 0712|MP0712|[212Pb]Pb-MP0712 | DLL3 Inhibitor 2 | 212Pb-MP0712 is a radioconjugate comprising a designed ankyrin repeat protein (DARPin) that specifically binds DLL3 conjugated to the radionuclide 212Pb, which potentially inhibits tumor growth (Cancer Res (2025) 85 (8_Supplement_1): 346). |
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07278479 | Phase Ib/II | 212Pb-MP0712 | Study of [212Pb]Pb-DOTAM-MAM279 ([212Pb]Pb-MP0712) in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors | Recruiting | USA | 0 |
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