Therapy Detail
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| Therapy Name | ASKG915 + Fruquintinib |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ASKG915 | ASKG 915|ASKG-915 | PD-L1/PD-1 antibody 136 | ASKG915 is an anti-PD-1/IL-15 prodrug fusion molecule that potentially induces antitumor immune activity (J Immunother Cancer 2022;10(Suppl 2):1183). | |
| Fruquintinib | Fruzaqla | HMPL-013 | VEGFR Inhibitor (Pan) 36 | Fruzaqla (fruquintinib) binds and inhibits VEGFR1/2/3, potentially resulting in reduced cell proliferation and decreased tumor growth (PMID: 25482937, PMID: 31790382). Fruzaqla (fruquintinib) is FDA approved for use in patients with metastatic colorectal cancer who have received prior therapy (FDA.gov). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05867420 | Phase Ib/II | ASKG915 + Fruquintinib ASKG915 ASKG915 + Bevacizumab + Paclitaxel ASKG915 + Docetaxel | A Study of ASKG915 in Patients With Selected Advanced Solid Tumors. | Recruiting | USA | 1 |
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