Therapy Detail
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| Therapy Name | VRN110755 |
| Synonyms | |
| Therapy Description |
VRN110755 is a brain-penetrant EGFR inhibitor with activity against EGFR mutations including C797S, which potentially inhibits growth of EGFR-mutant tumors (J Clin Oncol 2026 44: 16_suppl, 8623). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| VRN110755 | VRN 110755|VRN-110755 | EGFR Inhibitor 4th gen 21 | VRN110755 is a brain-penetrant EGFR inhibitor with activity against EGFR mutations including C797S, which potentially inhibits growth of EGFR-mutant tumors (J Clin Oncol 2026 44: 16_suppl, 8623). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07699328 | Phase Ib/II | VRN110755 | A Study of VRN110755 in Patients With EGFR-Mutant Non-Small Cell Lung Cancer (REACH-EGFR) | Recruiting | FRA | ESP | CAN | AUS | 6 |
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