Therapy Detail
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| Therapy Name | XNW28012 |
| Synonyms | |
| Therapy Description |
XNW28012 is an antibody-drug conjugate (ADC) comprising an antibody targeting F3 (TF; tissue factor) linked to a topoisomerase I inhibitor, which potentially induces DNA damage and apoptosis and inhibits tumor cell proliferation (Cancer Res (2026) 86 (7_Supplement): 4437). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| XNW28012 | XNW-28012|XNW 28012 | XNW28012 is an antibody-drug conjugate (ADC) comprising an antibody targeting F3 (TF; tissue factor) linked to a topoisomerase I inhibitor, which potentially induces DNA damage and apoptosis and inhibits tumor cell proliferation (Cancer Res (2026) 86 (7_Supplement): 4437). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07707674 | Phase I | XNW28012 | Phase I Open-Label Randomized Multicenter Study of XNW28012 Monotherapy in Metastatic Pancreatic Cancer | Not yet recruiting | USA | 0 |
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