Therapy Detail
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| Therapy Name | 177Lu-DTPA-omburtamab |
| Synonyms | |
| Therapy Description |
177Lu-DTPA-omburtamab is a radioconjugate comprising an antibody targeting CD276 (B7-H3) linked to lutetium-177, which potentially inhibits tumor growth (Journal for ImmunoTherapy of Cancer 2021; 9, Suppl 2, 397, NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| 177Lu-DTPA-omburtamab | lutetium Lu 177-DTPA-omburtamab|[177Lu]-DTPA-omburtamab|177Lu-DTPA omburtamab | CD276 Antibody 26 | 177Lu-DTPA-omburtamab is a radioconjugate comprising an antibody targeting CD276 (B7-H3) linked to lutetium-177, which potentially inhibits tumor growth (Journal for ImmunoTherapy of Cancer 2021; 9, Suppl 2, 397, NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07698899 | Phase I | 177Lu-DTPA-omburtamab | A Study of 177Lu-DTPA-Omburtamab in Children and Adolescents With Brain Cancer or Cancer That Has Spread to the Central Nervous System (CNS) | Recruiting | USA | 0 |
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