Therapy Detail
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| Therapy Name | AL58805 + AL8326 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| AL58805 | AL 58805|AL-58805 | mTOR Inhibitor 52 PI3K Inhibitor (Pan) 44 | Limited information is currently available on AL58805, a putative dual-target PI3K/mTOR inhibitor (Sep 2026). | |
| AL8326 | AL-8326|AL 8326 | Aurkb Inhibitors 22 FGFR Inhibitor (Pan) 26 VEGFR Inhibitor (Pan) 36 | AL8326 is a tyrosine kinase inhibitor that inhibits Aurora B, Fgfr, and Vegfr, potentially leading to disrupted chromosome segregation, impaired cell division, decreased tumor cell proliferation, and antitumor activity (J Clin Oncol 41, 2023 (suppl 16; abstr 8585), NCI Drug Dictionary). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT07811232 | Phase Ib/II | AL58805 + AL8326 AL58805 + Eribulin AL58805 + Fulvestrant | A Study of AL58805 in Advanced, Metastatic GYN, STS or Breast Cancers | Not yet recruiting | USA | 0 |
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