Therapy Detail
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| Therapy Name | TT-10 + TT-4 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| TT-10 | TT10|TT 10 | Adenosine Targeting 25 | TT-10 acts as an antagonist to the adenosine receptor A2AR, potentially leading to inhibition of tumor growth and enhanced antitumor immune response (Cancer Res (2022) 82 (12_Supplement): 3454) | |
| TT-4 | TT4|TT 4|PORT7|PORT-7|PORT 7 | Adenosine Targeting 25 | TT-4 acts as an antagonist to the adenosine receptor A2BR, which potentially inhibits tumor growth and induces antitumor immune response (Cancer Res (2022) 82 (12_Supplement): 3454). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04969315 | Phase Ib/II | TT-10 + TT-4 TT-4 TT-10 | TT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural Mesothelioma | Recruiting | USA | 0 |
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