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Therapy Name Olmutinib
Synonyms
Therapy Description

Olmutinib (BI1482694, HM61713) is a third-generation EGFR inhibitor that inhibits activating mutations in EGFR, including those occurring with T790M, and spares wild-type EGFR, potentially resulting in decreased tumor growth (PMID: 25027951, PMID: 25521095, PMID: 30356705, PMID: 32830792, PMID: 32679450).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Olmutinib HM61713|BI 1482694|BI1482694|BI-1482694 EGFR Inhibitor 3rd gen 28 Olmutinib (BI1482694, HM61713) is a third-generation EGFR inhibitor that inhibits activating mutations in EGFR, including those occurring with T790M, and spares wild-type EGFR, potentially resulting in decreased tumor growth (PMID: 25027951, PMID: 25521095, PMID: 30356705, PMID: 32830792, PMID: 32679450).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02485652 Phase II Olmutinib Phase II Trial of HM61713 for the Treatment of >= 2nd Line T790M Mutation Positive Adenocarcinoma of the Lung Terminated USA | ITA | ESP | DEU | CAN | AUS 4


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