Therapy Detail
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| Therapy Name | GDC-0810 |
| Synonyms | |
| Therapy Description |
Brilanestrant (GDC-0810) binds to estrogen receptors and promotes their degradation, potentially resulting in decreased growth of estrogen receptor-expressing tumor cells (PMID: 31266752). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| GDC-0810 | ARN-810|Brilanestrant|GDC0810|GDC 0810|ARN 810|ARN810|RO7056118 | Hormone - Anti-estrogens 31 | Brilanestrant (GDC-0810) binds to estrogen receptors and promotes their degradation, potentially resulting in decreased growth of estrogen receptor-expressing tumor cells (PMID: 31266752). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT01823835 | Phase II | GDC-0810 | A Study of ARN-810 (GDC-0810) in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer | Terminated | USA | NLD | ESP | 1 |
| NCT02569801 | Phase II | GDC-0810 Fulvestrant | A Study of GDC-0810 Versus Fulvestrant in Women With Advanced or Metastatic Breast Cancer Resistant to Aromatase Inhibitor Therapy | Terminated | USA | GBR | ESP | DEU | AUS | 1 |
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