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Therapy Name | Peginterferon alfa-2b |
Synonyms | |
Therapy Description |
Sylatron (peginterferon alfa-2b) is polyethylene glycol (PEG)-conjugated recombinant interferon alpha, subtype 2b, which may have antitumor activity (PMID: 23002124, PMID: 16953837, PMID: 24741445). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Peginterferon alfa-2b | Sylatron | PEG-IFN | Sylatron (peginterferon alfa-2b) is polyethylene glycol (PEG)-conjugated recombinant interferon alpha, subtype 2b, which may have antitumor activity (PMID: 23002124, PMID: 16953837, PMID: 24741445). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02038036 | Phase III | Peginterferon alfa-2b Anagrelide Hydroxyurea Pipobroman Ruxolitinib | Ruxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Available Therapy. (RESPONSE-2) | Completed | TUR | ITA | ISR | HUN | FRA | ESP | DEU | CAN | BEL | AUS | 2 |
NCT02089685 | Phase Ib/II | Ipilimumab Peginterferon alfa-2b Pembrolizumab | Safety and Tolerability of Pembrolizumab (MK-3475) + Pegylated Interferon Alfa-2b and Pembrolizumab+ Ipilimumab in Participants With Advanced Melanoma or Renal Cell Carcinoma (MK-3475-029/KEYNOTE-29) | Completed | 0 | |
NCT01964300 | Phase II | Peginterferon alfa-2b | Peginterferon Alfa-2b in Treating Younger Patients With Craniopharyngioma That is Recurrent or Cannot Be Removed By Surgery | Terminated | USA | 0 |
NCT02737046 | Phase II | Interferon alpha-2b Peginterferon alfa-2b Belinostat + Zidovudine | Belinostat Therapy With Zidovudine for Adult T-Cell Leukemia-Lymphoma | Active, not recruiting | USA | 0 |