Therapy Detail
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| Therapy Name | Yttrium Y-90 clivatuzumab tetraxetan |
| Synonyms | |
| Therapy Description |
Yttrium Y-90 clivatuzumab tetraxetan (IMMU-107) consists of an anti-MUC1 antibody conjugated to radioactive yttrium Y 90, which binds and delivers cytotoxic radiation to MUC1-expressing tumor cells (PMID: 26187510). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Yttrium Y-90 clivatuzumab tetraxetan | IMMU-107|90Y-hPAM4 | MUC1 Antibody 8 | Yttrium Y-90 clivatuzumab tetraxetan (IMMU-107) consists of an anti-MUC1 antibody conjugated to radioactive yttrium Y 90, which binds and delivers cytotoxic radiation to MUC1-expressing tumor cells (PMID: 26187510). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT01956812 | Phase III | Yttrium Y-90 clivatuzumab tetraxetan Gemcitabine | Phase 3 Trial of 90Y-Clivatuzumab Tetraxetan & Gemcitabine vs Placebo & Gemcitabine in Metastatic Pancreatic Cancer (PANCRIT-1) | Terminated | USA | POL | ISR | FRA | ESP | CAN | BEL | AUT | 0 |
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