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Therapy Name CHR-3996
Synonyms
Therapy Description

Tractinostat (CHR-3996) is a selective Class I HDAC inhibitor, which may result in decreased tumor growth (PMID: 22553374).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CHR-3996 VRx3996|Tractinostat|Nanatinostat HDAC Inhibitor 45 Tractinostat (CHR-3996) is a selective Class I HDAC inhibitor, which may result in decreased tumor growth (PMID: 22553374).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06302140 Phase I CHR-3996 CHR-3996 + Valganciclovir A Mass Balance Study of [14C]-Nanatinostat and Relative Bioavailability Study of Nanatinostat in Patients With Advanced Cancers Recruiting ESP 0
NCT05011058 Phase II CHR-3996 CHR-3996 + Valganciclovir An Open-Label, Phase 2 Trial of Nanatinostat in Combination With Valganciclovir in Patients With Epstein-Barr Virus-Positive (EBV+) Relapsed/Refractory Lymphomas (NAVAL-1) Recruiting USA | ITA | ISR | GBR | FRA | ESP | DEU | CAN | BRA | AUS 5


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