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Therapy Name | Efizonerimod |
Synonyms | |
Therapy Description |
Efizonerimod (MEDI6383) is a fusion protein that binds to TNFRSF4 (OX40, CD134) and mimics the binding of the ligand, TNFSF4 (OX40L, CD252), to stimulate proliferation of T-cells and enhance an anti-tumor response (Journal of Clinical Oncology 33, no. 15_suppl (May 20 2015) 3056-3056, PMID: 29545330). |