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Therapy Detail
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| Therapy Name | Ralimetinib |
| Synonyms | |
| Therapy Description |
Ralimetinib (LY2228820) is a selective ATP competitive inhibitor of p38 MAPK alpha (MAPK14) and beta (MAPK11), which inhibits tumor growth (PMID: 26581242, PMID: 24356814, PMID: 31791552, PMID: 31707688). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Ralimetinib | LY2228820|LY-2228820|LY 2228820 | p38-alpha Inhibitor 1 | Ralimetinib (LY2228820) is a selective ATP competitive inhibitor of p38 MAPK alpha (MAPK14) and beta (MAPK11), which inhibits tumor growth (PMID: 26581242, PMID: 24356814, PMID: 31791552, PMID: 31707688). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT01663857 | Phase Ib/II | Ralimetinib Carboplatin + Gemcitabine | A Study of LY2228820 for Recurrent Ovarian Cancer | Completed | USA | DEU | BEL | AUS | 0 |
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