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Therapy Detail
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| Therapy Name | CDX-0158 |
| Synonyms | |
| Therapy Description |
CDX-0158 (KTN0158) is a humanized anti-cKIT antibody that inhibits KIT signaling, resulting in inhibition of cell proliferation (Mol Cancer Ther December 2015 14; C167, PMID: 28138031). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| CDX-0158 | KTN0158|CDX 0158|KTN 0158 | KIT Inhibitor 57 | CDX-0158 (KTN0158) is a humanized anti-cKIT antibody that inhibits KIT signaling, resulting in inhibition of cell proliferation (Mol Cancer Ther December 2015 14; C167, PMID: 28138031). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02642016 | Phase I | CDX-0158 | A Study to Evaluate the Safety and Pharmacokinetics of KTN0158 in Adult Patients With Advanced Solid Tumors | Completed | USA | 0 |
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