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Therapy Name | Ad-RTS-IL-12 plus AL |
Synonyms | |
Therapy Description |
Ad-RTS-IL-12 plus AL is a replication incompetent adenovirus that initiates interleukin-12 (IL-12) production upon veledimex induction, which may stimulate anti-tumor immunity (NCI Drug Dictionary). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Ad-RTS-IL-12 plus AL | adenovirus-mediated human interleukin-12 INXN-2001 plus veledimex | Ad-RTS-IL-12 plus AL is a replication incompetent adenovirus that initiates interleukin-12 (IL-12) production upon veledimex induction, which may stimulate anti-tumor immunity (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02423902 | Phase Ib/II | Ad-RTS-IL-12 plus AL | A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Breast Cancer | Completed | USA | 0 |
NCT03330197 | Phase I | Ad-RTS-IL-12 plus AL | A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors or DIPG | Terminated | USA | 0 |
NCT02026271 | Phase I | Ad-RTS-IL-12 plus AL | A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma | Completed | USA | 0 |