Therapy Detail
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| Therapy Name | MK-1966 + Nelitolimod |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| MK-1966 | MK 1966 | MK-1966 down-regulates IL-10 activity and enhances anti-tumor immunity (NCI Drug Dictionary). | ||
| Nelitolimod | SD101|SD 101|SD-101 | TLR9 Agonist 9 | Nelitolimod (SD-101) is an oligonucleotide which interacts with Toll-Like Receptor 9 (TLR9) and activates memory T helper cells 1 (Th1) (PMID: 30154193, PMID: 31921384). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02731742 | Phase I | MK-1966 + Nelitolimod | Dose Evaluation of MK-1966 in Combination With SD-101 in Participants With Advanced Malignancies (MK-1966-001) | Terminated | 0 |
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