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Therapy Name ADXS31-164
Synonyms
Therapy Description

ADXS31-164 comprises a live-attenuated Listeria monocytogenes strain engineered to express a fusion protein containing Erbb2 (Her2) epitopes and a fragment of the listeriolysin O (LLO) protein, which may induce an anti-tumor immune response (PMID: 20725099).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
ADXS31-164 ADXS 31164|ADXS-HER2|OST-HER2|OST31 164|OST31164|OST31-164 ADXS31-164 comprises a live-attenuated Listeria monocytogenes strain engineered to express a fusion protein containing Erbb2 (Her2) epitopes and a fragment of the listeriolysin O (LLO) protein, which may induce an anti-tumor immune response (PMID: 20725099).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04974008 Phase II ADXS31-164 Osteosarcoma Maintenance Therapy With OST31-164 (OST-164-01) Completed USA 0
NCT02386501 Phase Ib/II ADXS31-164 Dose Escalation Study of ADXS31-164 in Subjects With HER2 Expressing Solid Tumors Completed USA 0


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