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Therapy Name Vopratelimab
Synonyms
Therapy Description

Vopratelimab (JTX-2011) is a humanized monoclonal antibody against ICOS (inducible co-stimulator molecule) that regulates anti-tumor immune response (Cancer Res 2016;76(14 Suppl):Abstract nr 573).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Vopratelimab JTX2011|JTX-2011 Vopratelimab (JTX-2011) is a humanized monoclonal antibody against ICOS (inducible co-stimulator molecule) that regulates anti-tumor immune response (Cancer Res 2016;76(14 Suppl):Abstract nr 573).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04319224 Phase Ib/II Vopratelimab Nivolumab + Vopratelimab Ipilimumab + Vopratelimab Vopratelimab (JTX-2011) Alone and in Combination With Anti-PD-1 or Anti-CTLA-4 in Subjects With Advanced and/or Refractory Solid Tumors Terminated USA 0
NCT02904226 Phase Ib/II Nivolumab + Vopratelimab Vopratelimab Dose Escalation and Expansion of JTX-2011 Alone or in Combination With Anti-PD-1 in Subjects With Advanced Solid Tumors (ICONIC) Completed USA 0


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