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Therapy Name BMS-986148
Synonyms
Therapy Description

BMS-986148 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against mesothelin (MSLN) linked to the anti-microtubule agent tubulysin, which may result in cytotoxic effects in mesothelin-expressing tumor cells (PMID: 34615718).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BMS-986148 BMS986148|BMS 986148 MSLN Antibody 12 BMS-986148 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody against mesothelin (MSLN) linked to the anti-microtubule agent tubulysin, which may result in cytotoxic effects in mesothelin-expressing tumor cells (PMID: 34615718).

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02341625 Phase Ib/II BMS-986148 BMS-986148 + Nivolumab A Study of BMS-986148 in Patients With Select Advanced Solid Tumors Terminated USA | NLD | ITA | GBR | CAN | BEL | AUS 0


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