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Therapy Name EGFR(V)-EDV-Dox
Synonyms
Therapy Description

EGFR(V)-EDV-Dox is a formulation of EGFR bispecific antibodies coupled with nanocellular compounds containing therapeutic dose of doxorubicin, which delivers the cytotoxic doxorubicin to tumor cells over expressing EGFR, leading to anti-tumor activities (PMID: 26279503).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
EGFR(V)-EDV-Dox EGFR Antibody 60 EGFR(V)-EDV-Dox is a formulation of EGFR bispecific antibodies coupled with nanocellular compounds containing therapeutic dose of doxorubicin, which delivers the cytotoxic doxorubicin to tumor cells over expressing EGFR, leading to anti-tumor activities (PMID: 26279503).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT02766699 Phase I EGFR(V)-EDV-Dox A Study to Evaluate the Safety, Tolerability and Immunogenicity of EGFR(V)-EDV-Dox in Subjects With Recurrent Glioblastoma Multiforme (GBM) (CerebralEDV) Unknown status USA 0


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