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Therapy Name | TTI-621 |
Synonyms | |
Therapy Description |
TTI-621 (ontorpacept) is a fusion protein consisting of the CD47 binding domain of SIRPalpha linked to the IgG1 Fc domain, which potentially enhances phagocytosis of tumor cells and inhibits tumor growth (PMID: 27856600, PMID: 33451977). |