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Therapy Detail
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| Therapy Name | Budigalimab |
| Synonyms | |
| Therapy Description |
Budigalimab is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 32770720). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Budigalimab | ABBV181|ABBV 181|ABBV-181 | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 124 | Budigalimab is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 32770720). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03000257 | Phase I | Budigalimab | A Study of ABBV-181 in Participants With Advanced Solid Tumors | Completed | USA | FRA | FIN | ESP | CAN | BEL | AUT | AUS | 2 |
| NCT03818542 | Phase I | ABBV-927 ABBV-368 Budigalimab | A Study to Assess the Effects of Multiple Study Drug Regimens in Subjects With Newly Diagnosed Locally Advanced Head and Neck Squamous Cell Carcinoma | Terminated | USA | 0 |
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