Therapy Detail
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| Therapy Name | BMX-001 + Temozolomide |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| BMX-001 | BMX-001 is a human mitochondrial manganese superoxide dismutase (MnSOD) mimetic that clears reactive oxygen species upon cellular internalization, thereby potentially reducing the degree of chemotoxicity within healthy tissue (PMID: 29464912). | |||
| Temozolomide | Temodar | Methazolastone|TMZ | Chemotherapy - Alkylating 18 | Temodar (temozolomide) is a dacarbazine analog and cytotoxic alkylating agent (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02655601 | Phase Ib/II | BMX-001 + Temozolomide Temozolomide | Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001 | Completed | USA | 0 |
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