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Therapy Name | INO-1400 + INO-9012 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
INO-1400 | INO-1400 is a plasmid encoding TERT with two mutations, which may increase anti-tumor immune response against hTERT-expressing tumor cells (PMID: 29081765). | |||
INO-9012 | INO9012|INO 9012 | INO-9012 is a plasmid encoding IL-12 protein subunits, p35 and p40, which may increase anti-tumor immune response (AACR; Cancer Res 2019;79(13 Suppl):Abstract nr CT114, PMID: 32208168). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02960594 | Phase I | INO-1400 + INO-9012 INO-1400 | hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse | Completed | USA | 0 |