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Therapy Name | INO-3106 + INO-9012 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
INO-3106 | INO-3106 is a plasmid comprising E6 and E7 of HPV-6, which may result in antitumor activity via induction of a cytotoxic T-lymphocyte immune response against tumor cells (PMID: 32013270). | |||
INO-9012 | INO9012|INO 9012 | INO-9012 is a plasmid encoding IL-12 protein subunits, p35 and p40, which may increase anti-tumor immune response (AACR; Cancer Res 2019;79(13 Suppl):Abstract nr CT114, PMID: 32208168). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02241369 | Phase I | INO-3106 + INO-9012 | Immunotherapy in Subjects With HPV-6 Associated Aerodigestive Precancerous Lesions and Malignancies | Completed | USA | 0 |