Therapy Detail
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| Therapy Name | INO-3106 + Rocakinogene sifuplasmid |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| INO-3106 | INO-3106 is a plasmid comprising E6 and E7 of HPV-6, which may result in antitumor activity via induction of a cytotoxic T-lymphocyte immune response against tumor cells (PMID: 32013270). | |||
| Rocakinogene sifuplasmid | INO9012|INO 9012|INO-9012 | Rocakinogene sifuplasmid (INO-9012) is a plasmid encoding the IL-12 protein subunits p35 and p40, which may increase antitumor immune response and decrease tumor growth (AACR; Cancer Res 2019;79(13 Suppl):Abstract nr CT114, PMID: 32208168). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Case insensitive filtering will display rows if any text in any cell matches the filter term
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02241369 | Phase I | INO-3106 + Rocakinogene sifuplasmid | Immunotherapy in Subjects With HPV-6 Associated Aerodigestive Precancerous Lesions and Malignancies | Completed | USA | 0 |
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