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Therapy Name MK-5890
Synonyms
Therapy Description

MK-5890 is monoclonal antibody that targets CD27, potentially resulting in increased T-cell dependent immune responses, and antitumor activity (Journal for ImmunoTherapy of Cancer 2020;8).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
MK-5890 CD27 Antibody 3 MK-5890 is monoclonal antibody that targets CD27, potentially resulting in increased T-cell dependent immune responses, and antitumor activity (Journal for ImmunoTherapy of Cancer 2020;8).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03396445 Phase I MK-5890 MK-5890 + Pembrolizumab Safety and Pharmacokinetics Study of MK-5890 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Adults With Advanced Solid Tumors (MK-5890-001) Completed USA | NLD | ISR | ESP 3


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