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Therapy Name | Budigalimab + SC-003 |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Budigalimab | ABBV181|ABBV 181|ABBV-181 | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 | Budigalimab is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 32770720). | |
SC-003 | SC003|SC 003|Tamrintamab pamozirine | Tamrintamab pamozirine (SC-003) is a monoclonal anti-tumor-associated antigen (TAA) antibody in conjugation with an undisclosed cytotoxic agent, which may target TAA-expressing tumor cells (PMID: 32513564). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02539719 | Phase I | Budigalimab + SC-003 SC-003 | Study of SC-003 Alone and in Combination With ABBV-181 in Subjects With Platinum-Resistant/Refractory Ovarian Cancer | Terminated | USA | 0 |