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Therapy Name BA3021
Synonyms
Therapy Description

BA3021 (CAB-ROR2-ADC) is a conditionally active anti-ROR2 antibody in conjugation with a cytotoxic agent that preferentially binds and delivers cytotoxicity to Ror2-expressing cells in tumors, which potentially induces antitumor activity (Cancer Res (2018) 78 (13_Supplement): 833).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BA3021 CAB-ROR2-ADC|BA 3021|Ozuriftamab Vedotin BA3021 (CAB-ROR2-ADC) is a conditionally active anti-ROR2 antibody in conjugation with a cytotoxic agent that preferentially binds and delivers cytotoxicity to Ror2-expressing cells in tumors, which potentially induces antitumor activity (Cancer Res (2018) 78 (13_Supplement): 833).

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03504488 Phase Ib/II BA3021 CAB-ROR2-ADC Safety and Efficacy Study in Patients With Solid Tumors Active, not recruiting USA | POL | GRC | ESP 2
NCT05271604 Phase II BA3021 A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Recruiting USA 0


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