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Therapy Name OKN-007
Synonyms
Therapy Description

OKN-007 is a small molecule nitrone inhibitor that can cross the blood brain barrier, and may result in anti-inflammatory and apoptotic activity (PMID: 26248280, PMID: 31628293).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
OKN-007 OKN007|OKN 007 OKN-007 is a small molecule nitrone inhibitor that can cross the blood brain barrier, and may result in anti-inflammatory and apoptotic activity (PMID: 26248280, PMID: 31628293).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05518838 Expanded access OKN-007 Expanded Access to OKN-007 for Patients With Diffuse Midline Glioma, H3 K27-altered No longer available USA 0
NCT05561374 Phase I OKN-007 Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients With Recurrent High-Grade Glioma Active, not recruiting USA 0
NCT01672463 Phase I OKN-007 Clinical Trial of IV OKN-007 in a Pilot Cohort of Human Recurrent Malignant Glioma Patients Active, not recruiting USA 0


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