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| Therapy Name | CF102 |
| Synonyms | |
| Therapy Description |
Namodenoson (CF102) is an A3 adenosine receptor agonist (ADORA3), which potentially induces tumor cell apoptosis (PMID: 21660967). |
| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| CF102 | Namodenoson|2-Cl-IB-MECA|Chloro-IB-MECA|CF-102 | Namodenoson (CF102) is an A3 adenosine receptor agonist (ADORA3), which potentially induces tumor cell apoptosis (PMID: 21660967). |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05201404 | Phase III | CF102 | Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis (LIVERATION) | Recruiting | USA | SVK | ROU | POL | ISR | BGR | 3 |
| NCT02128958 | Phase II | CF102 | Phase 2, Randomized, Double-Blind, Placebo-Controlled of the Efficacy and Safety of CF102 in Hepatocellular Carcinoma (HCC) | Completed | USA | ROU | ISR | BGR | 1 |
| NCT06387342 | Phase II | CF102 | Namodenoson Treatment of Advanced Pancreatic Cancer | Recruiting | ISR | 0 |