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Therapy Name | CF102 |
Synonyms | |
Therapy Description |
Namodenoson (CF102) is an A3 adenosine receptor agonist (ADORA3), which potentially induces tumor cell apoptosis (PMID: 21660967). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
CF102 | Namodenoson|2-Cl-IB-MECA|Chloro-IB-MECA|CF-102 | Namodenoson (CF102) is an A3 adenosine receptor agonist (ADORA3), which potentially induces tumor cell apoptosis (PMID: 21660967). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT05201404 | Phase III | CF102 | Namodenoson in the Treatment of Advanced Hepatocellular Carcinoma in Patients With Child-Pugh Class B7 Cirrhosis (LIVERATION) | Recruiting | USA | SVK | ROU | POL | ISR | BGR | 3 |
NCT02128958 | Phase II | CF102 | Phase 2, Randomized, Double-Blind, Placebo-Controlled of the Efficacy and Safety of CF102 in Hepatocellular Carcinoma (HCC) | Completed | USA | ROU | ISR | BGR | 1 |
NCT06387342 | Phase II | CF102 | Namodenoson Treatment of Advanced Pancreatic Cancer | Not yet recruiting | ISR | 0 |