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Therapy Name CPX-POM
Synonyms
Therapy Description

CPX-POM (fosciclopirox) is a prodrug of ciclopirox with increased bioavailability, which may inhibit tumor cell proliferation and decrease tumor growth (Cancer Res 2018;78 (13 Suppl):Abstract nr 5882, PMID: 31113837).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CPX-POM CPXPOM|CPX POM|Fosciclopirox CPX-POM (fosciclopirox) is a prodrug of ciclopirox with increased bioavailability, which may inhibit tumor cell proliferation and decrease tumor growth (Cancer Res 2018;78 (13 Suppl):Abstract nr 5882, PMID: 31113837).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03348514 Phase I CPX-POM Safety, Dose Tolerance, Pharmacokinetics, and Pharmacodynamics Study of CPX-POM in Patients With Advanced Solid Tumors Completed USA 0
NCT04608045 Phase I CPX-POM Safety, Dose Tolerance, Pharmacokinetics, and Pharmacodynamics Study of CPX-POM in Patients With Advanced Solid Tumors Completed USA 0
NCT04525131 Phase II CPX-POM Safety, Dose Tolerance, Pharmacokinetics, Pharmacodynamics of CPX-POM in Patients With Newly Diagnosed or Recurrent Bladder Tumors Completed USA 0


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