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Therapy Name Anti-BCMA CAR-T cells
Synonyms
Therapy Description

Anti-BCMA CAR-T cells are T-cells engineered to express a chimeric antigen receptor (CAR) targeting BCMA, which may enhance antitumor immune response (PMID: 23344265).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Anti-BCMA CAR-T cells CART-BCMA|CT053 TNFRSF17 Immune Cell Therapy 27 Anti-BCMA CAR-T cells are T-cells engineered to express a chimeric antigen receptor (CAR) targeting BCMA, which may enhance antitumor immune response (PMID: 23344265).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT03338972 Phase I Cyclophosphamide + Fludarabine Anti-BCMA CAR-T cells Immunotherapy With BCMA CAR-T Cells in Treating Patients With BCMA Positive Relapsed or Refractory Multiple Myeloma Completed USA 0
NCT07200089 Phase I Anti-BCMA CAR-T cells Anti-BCMA CAR-T cells + NT-I7 Recombinant Human IL-7 (NT-I7) in Relapsed/Refractory Multiple Myeloma Following BCMA CAR-T Therapy (Cilta-cel) Not yet recruiting USA 0
NCT03915184 Phase I Anti-BCMA CAR-T cells Clinical Trial to Evaluate CT053 in Patients With Relapsed and/or Refractory Multiple Myeloma Active, not recruiting USA | CAN 0


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