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Therapy Name | Phenelzine |
Synonyms | |
Therapy Description |
Nardil (phenelzine) is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) that also inhibits Kdm1a (Lsd1), which may lead to inhibition of stem cell growth through epigenetic regulation (PMID: 26748182). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Phenelzine | Nardil | Nardelzine|Beta-phenylethylhydrazine | KDM1A Inhibitor 15 | Nardil (phenelzine) is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) that also inhibits Kdm1a (Lsd1), which may lead to inhibition of stem cell growth through epigenetic regulation (PMID: 26748182). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT02217709 | Phase II | Phenelzine | Phenelzine Sulfate in Treating Patients With Non-metastatic Recurrent Prostate Cancer | Completed | USA | 0 |