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Therapy Name | Ibudilast + Temozolomide |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Ibudilast | AV411|MN166|MN-166 | Ibudilast (MN-166) is a small molecule inhibitor of macrophage migration inhibitory factor (MIF), which may decrease tumor cell proliferation and cell migration (PMID: 30814573, PMID: 20534506). | ||
Temozolomide | Temodar | Methazolastone|TMZ | Chemotherapy - Alkylating 18 | Temodar (temozolomide) is a dacarbazine analog and cytotoxic alkylating agent (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT03782415 | Phase Ib/II | Temozolomide Ibudilast + Temozolomide | Study to Evaluate Ibudilast and TMZ Combo Treatment in Recurrent GBM | Active, not recruiting | USA | 0 |