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Therapy Name Anti-SLAMF7 CAR T cells
Synonyms
Therapy Description

Anti-SLAMF7 CAR T cells are T-cells that express a chimeric antigen receptor derived from the SLAMF7 (CS1)-targeting antibody elotuzumab, which potentially results in anti-tumor activity against SLAMF7-expressing tumor cells (PMID: 29089311).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Anti-SLAMF7 CAR T cells Autologous Anti-SLAMF7 CAR T-cells|SLAMF7 CAR-T cells Anti-SLAMF7 CAR T cells are T-cells that express a chimeric antigen receptor derived from the SLAMF7 (CS1)-targeting antibody elotuzumab, which potentially results in anti-tumor activity against SLAMF7-expressing tumor cells (PMID: 29089311).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04499339 Phase Ib/II Anti-SLAMF7 CAR T cells A Phase I/IIa Clinical Trial to Assess Feasibility, Safety and Antitumor Activity of Autologous SLAMF7 CAR-T Cells in Multiple Myeloma Active, not recruiting FRA | ESP | DEU 0


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