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Therapy Name | Sunvozertinib |
Synonyms | |
Therapy Description |
Zegfrovy (sunvozertinib) is an irreversible EGFR inhibitor that preferentially inhibits mutant EGFR and ERBB2 (HER2), which may lead to growth inhibition of tumor cells with EGFR activation (AACR Annual Meeting 2019, Abstract 3081, PMID: 35404393). Zegfrovy (sunvozertinib) is FDA-approved for use in patients with locally advanced or metastatic non-small cell lung cancer harboring EGFR exon 20 insertions (FDA.gov). |