Therapy Detail
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| Therapy Name | Nab-paclitaxel + ORIC-101 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Nab-paclitaxel | Abraxane | ABI-007|Paclitaxel Protein-bound | Chemotherapy - Taxane 3 | Abraxane (nab-paclitaxel) is an albumin-stablized version of paclitaxel, which binds microtubules and prevents depolymerization, resulting in decreased cell motility and division (NCI Drug Dictionary). |
| ORIC-101 | ORIC101|ORIC 101 | GR Antagonist 2 | ORIC-101 is an antagonist of the glucocorticoid receptor (GR), which has potential antitumor activity (PMID: 30091920). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03928314 | Phase I | Nab-paclitaxel + ORIC-101 | Study of ORIC-101 in Combination With Anticancer Therapy | Terminated | USA | 0 |
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