Therapy Detail
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| Therapy Name | Mezagitamab |
| Synonyms | |
| Therapy Description |
Mezagitamab (TAK-079) is a monoclonal antibody that targets CD38, which has potential cytolytic effects against CD38-expressing cells (J Immunol May 1, 2017, 198 (1 Supplement) 224.20, PMID: 32045493). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Mezagitamab | TAK079|TAK 079|TAK-079 | CD38 Antibody 21 | Mezagitamab (TAK-079) is a monoclonal antibody that targets CD38, which has potential cytolytic effects against CD38-expressing cells (J Immunol May 1, 2017, 198 (1 Supplement) 224.20, PMID: 32045493). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT03439280 | Phase Ib/II | Dexamethasone + Mezagitamab + Pomalidomide Mezagitamab | A Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of TAK-079 Administered Subcutaneously as a Single Agent in Participants With Relapsed/Refractory (r/r) Multiple Myeloma (MM) | Completed | USA | 0 |
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